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To view or add a comment, sign in GSK2798745 A rare journey of a TRPV4 antagonist in the clinic TRPV4 has long attracted attention in respiratory disease, heart failure, and lung injury, yet only one small-molecule antagonist, GSK2798745, progressed into human studies

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[9] Lymphoplasmacytic lymphoma (also known as Waldenstrm macroglobulinemia) is a B cell malignancy with hematologic changes that affect the lymphatic system

According to the author, Unfortunately, the FDA has no jurisdiction over patent law and no power to immunize compounding pharmacies from liability for patent infringementthe Patent Act grants patentees a private right to enforce their patents and a remedy for infringement. In short, the likelihood of success for a patent infringement case appears to be in dispute, especially given that this is a largely untested line of attack that pharmaceutical companies have not traditionally taken against compounders thus far