is it normal to gain weight on glp 1 Wegovy: Causes and Solutions Surprising Causes of Weight Gain

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Clinical trial data and post-marketing surveillance have not confirmed an increased incidence of medullary thyroid carcinoma in GLP-1RA-treated patients, though long-term monitoring continues [30,31]

It nudges the pancreas to put out insulin, tells the brain that youre full, and slows down how quickly the stomach empties

Furthermore, obesity and T2DM lead to systemic inflammation, increasing pro-inflammatory brain cytokines, which may, in turn, interfere with insulin signaling and neurotransmission [92]