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Big move in obesity pharmacotherapy Novo Nordisk has submitted CagriSema to the FDA the first fixed-dose, once-weekly GLP-1 + amylin combination

Unlike FDA-approved medications (e.g., Wegovy, Ozempic, Zepbound), compounded alternatives lack agency review for safety, quality, and efficacy

Women prescribed a GLP-1 receptor agonist up to 2 years before conception were less likely to develop hypertensive disorders of pregnancy, gestational diabetes, have a preterm birth or cesarean delivery, researchers reported.“Relatively little is known how preconception GLP-1 receptor agonist use may impact pregnancy outcomes,&rdquo