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doi: 10.2147/COPD.S350133

The medication's effect on gastric emptying is most pronounced after the initial doses and tends to diminish over time with continued treatment

Nonetheless, the underlying reasons for the inconsistencies in the reported associations between T2DM and levels of plasma DPP-4 activity (lower, unaltered, higher) have not been adequately explained, although one study did suggest that it might be related to the populations studied, with changes only becoming evident once moderate or severe hyperglycaemia becomes established (68)
