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astrazeneca glp 1 AZ to terminate once-daily cotadutide program to focus on weekly GLP-1RA co-agonist AstraZeneca drops another GLP-1 after
Description
So the argument to be made is using the lowest GLP-1 dose possible to elicit gradual weight loss over time while optimizing diet, resistance exercise, etc

Metabolism 62, 347351 (2013)

Slower Digestion: It slows down how quickly food leaves your stomach
Further mechanistic studies were initiated investigating whether SAR425899 targets the GCGR including effects on energy expenditure and amino acid patterns
