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Moreover, the available reports do not allow confident separation of direct drug-related reproductive effects from mediation through weight loss and improvement in insulin resistance

Access, Cost and Shifting Landscape As people on these agents meet their weight and diabetes goals, there is concern that insurance companies will reduce or stop coverage given the high price tag of lifelong incretin therapy

It signals how quickly a high-demand therapy can upend established care patternsand how similar innovations may emerge in the years ahead

Pandey S, Mangmool S, Madreiter-Sokolowski CT, Wichaiyo S, Luangmonkong T, Parichatikanond W (2023) Exendin-4 protects against high glucose-induced mitochondrial dysfunction and oxidative stress in SH-SY5Y neuroblastoma cells through GLP-1 receptor/Epac/Akt signaling
