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Depending on the medication and individual response, patients typically lose between 10-20% of their body weight

Recent clinical trials demonstrating the efficacy of newer GLP-1 medicines across a broader range of diseases raise a fundamental question in GLP-1 pharmacology: Is metabolic control alone sufficient to explain such broad efficacy

-Cell hyperplasia also occurs with high-fat diet and this precedes -cell mass expansion (59), and in both human and mouse islets there is positive correlation between islet levels of GLP-1 and adiposity (138)

Balancing your medication with healthy GI transit requires an individualized strategy