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Short-chain fatty acid production- When gut bacteria ferment prebiotic fiber they produce compounds that signal fullness and help regulate fat storage

Moreover, the key circuits and neurotransmitters should be explored, whereby the GABAergic system is a candidate that deserves attention, given that GLP-1R is located presynaptically on such nerve terminals (Rebosio et al., 2018)

Comparative study on efficacy of empagliflozin versus sitagliptin, as an add-on therapy to metformin in Type 2 diabetic patients, J Pharm Bioallied Sci (2024) A comparison of the effects of empagliflozin and sitagliptin, when combined with metformin, on lipid levels in patients with Type 2 diabetes: A clinical investigation, Cureus (2023) Highlights of prescribing information, Merck Sharp & Dohme Corp

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