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[00:01:52] Emily Field: So today were gonna unpack this conversation in a very practical way

Between Q4 2024 and Q1 2025, the share of Medicare patients with comorbid diabetes or obesity and MASLD who started a GLP1 rose from 13% to 19%, compared with only a modest increase from 20% to 22% among commercially insured patients

These medications work by mimicking the bodys natural hormone GLP-1, which helps regulate appetite, blood sugar, and digestion

And that was a wild moment because that occurred almost simultaneously with an observation we had made with some colleagues in Korea, where I have an appointment, that when we were subjecting animals to a chronic stress its a chronic stress paradigm, again for those maybe less familiar, depression is a condition of abnormal stress response and we try to recapitulate that in the environment in an animal model