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DPP-4 inhibitors double the circulating concentrations of both GLP-1 and GIP

Mering and Minkowski's findings encouraged Gustave-douard Laguesse, a French histologist and pathologist, to theorise in 1893 that the pancreatic islets described by Langerhans produced an endocrine secretion (Hoet)

Each technology offers potential benefits like improved bioavailability or better absorption sites, but also faces challenges such as manufacturing difficulties, high costs, and regulatory hurdles
