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In preclinical in vitro work, GIPR signalling has been associated with lipid partitioning in adipocyte models and potentiation of insulin secretion under hyperglycaemic conditions

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Studies show that people taking GLP-1-based therapy (including exenatide, liraglutide, dulaglutide, semaglutide, or tirzepatide) are four times more likely to have food stuck in their stomachs during endoscopy (13.6% versus 2.3% in non-users) [6]