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Furthermore, the expanding investigation of semaglutide in Alzheimer's disease through the EVOKE Plus trial program, anticipated to report results by 2026 and 2027, represents a potentially enormous new indication that could add tens of millions of patients to the addressable treatment population globally, with corresponding API volume requirements that dwarf those of the existing obesity and diabetes indications

WT:Gnas fl/fl [saline] p = 0.0413

If gastroparesis is not treated, it could contribute to malnutrition, dehydration, the formation of a bezoar (a solid mass inside the stomach), and a host of other health problems

The US interchangeability designation requires switching studies costing an estimated $20-40 million per product