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Description
Tirzepatide liver-fat and body-composition MRI substudy SURPASS-3, relative liver-fat reduction -29.8/-39.6/-47.1% at 5/10/15 mg vs insulin degludec -11.2%: Gastaldelli Lancet D&E 2022

It's about ruling out the more probable, benign explanations before attributing a novel effect to the compound itself

Laboratory testing and imaging are used to confirm the diagnosis, and early recognition improves outcomes

Insulin sensitivity improvements at 15 mg are substantial
