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Laboratory and imaging tests are carried out after physical tests to diagnose the presence of kidney stones

This is particularly important as retatrutide is a relatively new medication, and understanding the nuances of its dosing can significantly impact its effectiveness

The primary estimand evaluated the treatment effect of the primary endpoint for all randomised participants, irrespective of adherence to trial product, initiation of non-randomised insulin treatment or addition of other non-insulin glucose-lowering medications (for more than 2 weeks) (i.e