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Aims/hypothesis A protective role of sodiumglucose cotransporter 2 inhibitors (SGLT2is) and glucagon-like peptide 1 receptor agonists (GLP1-ra) in the development of diabetic retinopathy and diabetic macular oedema has been described in some recent studies, which may extend beyond glycaemic control

Weight loss from GLP-1 can affect thyroid hormone absorption and metabolism, requiring closer clinical oversight and potential levothyroxine ad

GLP-1 drugs such as semaglutide are reshaping treatment of obesity, diabetes and cardiovascular disease with broader physiological effects now emerging.

Instead of focusing on the mythology behind a slow metabolism or the oversimplification of "eat less to burn more," it is essential to acknowledge that metabolism is complex and flexible and is influenced by hormones, lifestyle habits, and revolutionary medical studies