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We examined the effects of d-allulose on feeding behavior including arrhythmic hyperphagia that is characteristically associated with obesity and diabetes 3,4 and on glucose metabolism by glucose tolerance test (GTT), insulin tolerance test (ITT), and pyruvate tolerance test (PTT), and explored underlying mechanisms involving GLP-1 release and vagal afferents using Glp1r knockout mice ( Glp1r KO), surgical vagotomy and Glp1r knockdown specifically in vagal afferents using viral-mediated shRNA

In an exclusive interview with the ABC's Four Corners program for an investigation to air later this year, TGA chief medical advisor, adjunct professor Robyn Langham, explained the regulator's concerns

August 19, 2025: Judge Decides Which Rybelsus Claims Can Continue and Which Need to Be Refiled Novo Nordisk had filed a motion to dismiss, attempting to throw out many of the claims made by patients who took Rybelsus and developed complications like gastroparesis