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The area is favorable due to properly developed healthcare facilities, excellent access of patients to new treatment methods and the high insurance coverage on treating obesity that facilitates quick dissemination of new medications
Similar to this, in a meta-analysis study including 6 randomized controlled trials, Huang et al
Schematic representation of the main pathophysiological mechanisms (lipotoxicity, oxidative stress, inflammation, and gut-liver axis) and therapies under evaluation directed at these processes, including THR- agonists, FGF-21 analogs, pan-PPAR modulators, GLP-1 RAs, and GLP-1/GIP combinations, in addition to conventional treatments such as SGLT-2 inhibitors, metformin, statins, and vitamin E
Replacement of the C-terminal Trp-cage of exendin-4 with a fatty acid improves therapeutic utility
