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Odds of gastrointestinal events were similar between tirzepatide and GLP-1 RAs, except for diarrhoea with tirzepatide 10 mg (OR 1.51 [95% CI 1.07, 2.15], I 2 0%) (Table 2)

The FDA-approved doses for Mounjaro and Zepbound escalate in 2.5 mg steps: 2.5, 5, 7.5, 10, 12.5, and 15 mg

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