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CV primary is a composite of cardiovascular death, non-fatal MI, non-fatal stroke, and heart-failure events

The high incidence and prevalence are attributed to the ageing population and poor lifestyles (Minari et al., 2023)

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T-RDN inhibited GLP-1 mediated activation of efferent renal sympathetic nerve, thereby eliciting an enhanced diuresis and natriuresis, and increases in CrCl in HF
