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Jim Eggeman, a 911 operator in Ohio, said that before taking semaglutide, I could sit down and eat a large pizza, and now its one to two pieces at the most. He started on the drug for diabetes after a heart attack in December 2019 and lost 35 pounds, bringing his weight to 220

There is also preclinical evidence that GLP-1RAs may directly modulate pain through reduction of central sensitization, suggesting the possibility of additional symptomatic improvement for IIH patients with headache (32)

MG is an essential source of intracellular AGEs and abnormal accumulation of MG has been implicated in causing damage in various tissues and organs 3

Interestingly, one US survey found that while just under half (45 per cent) of adults would be interested in taking a safe and effective weight-loss drug, this interest dropped to just 14 per cent when they were informed that weight regain would occur upon stopping the drug