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In addition, the occurrence of the A allele of the SNP10010131, which is related to GLP-1-induced insulin secretion [74], was found to be associated with relatively greater bodyweight loss [73]

CrossRef Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes Jinsoo Song, In-Jeoung Baek, Sujeong Park, Jinjoo Oh, Deokha Kim, Kyung Song, Mi Kyung Kim, Hye Won Lee, Byoung Kuk Jang, Eun-Jung Jin iScience.2022

Taken altogether, these findings underscore the growing potential of dual/multi-agonist therapies to target the cardiometabolic phenotype closely linked to HFpEF

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