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New side effects, particularly dysesthesia, may appear even if you tolerated the other medications well

10.1056/NEJM199205143262003

glucagon receptor activation stimulates -oxidation of fatty acids, reducing hepatic lipid content, while GLP-1 enhances systemic insulin sensitivity and decreases lipolysis in adipose tissue, thereby indirectly reducing hepatic fat influx (51)

16 To ensure that the severity of DR did not confound the study results for the preexisting DR subgroup, we did a look-back on individuals with vs without GLP-1 RA prescriptions to assess the number of individuals with varying severity of DR at baseline