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Temporal differences between activation of LKB1 and inhibition of the incretin-induced Ca 2+ response were observed after treatments with metformin, suggesting that activation of LKB1 precedes downstream signals

The FDA has approved six prescription medications for use in people with a BMI over 30 or a BMI over 27 when a patient has additional obesity-related conditions

Of course, anything that addresses weight loss and lowering blood sugar levels will get my attention because I recognize that obesity and insulin resistance is at the root of almost all health conditions I see

However, the choice between the two medications should be made on an individual basis, considering factors such as patient characteristics, treatment goals, and potential side effects