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These are not FDA-approved yet, but they suggest more oral options may be coming

In that study, which is one of the largest CV outcome trials in the field of obesity, semaglutide at a dose of 2.4 mg once weekly is being evaluated to reduce CV events in people with overweight or obesity and previous CVD but without diabetes [71]

Semaglutides direct CV benefits stem from its anti-inflammatory properties, as it reduces systematic inflammation, lowers CV damage, and slows the progression of CVD [36]

Gastrointestinal side effectsincluding diarrhoea, nausea, and altered bowel frequencyare amongst the most frequently reported reactions