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Key takeaway: GLP-1 RAs do not appear to increase pancreatitis risk, and may be associated with improved outcomes if pancreatitis occurs.

FDA Enforcement Actions and Safety Concerns In September 2025, the FDA issued over 50 warning letters to compounders marketing GLP-1 products as generic equivalents to FDA-approved drugs

This is why anyone considering, using or prescribing GLP-1 medication should pair it with: Progressive resistance training (Jensen 2024) High-quality protein at each meal (Phillips & Paddon-Jones 2023) Lower-glycaemic, minimally processed foods (Ludwig & Ebbeling 2022) Adequate sleep and stress management (Walker 2020) These behaviours protect muscle, bone, metabolic rate and long-term health things the medication cannot do on its own

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