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Description
The weight loss effects of these agents have been known for some time, however, semaglutide appears to be the "best-in-class" GLP-1 RA for weight loss

doi: 10.1016/S0140-6736(07)61721-8
Approach this category with extra scrutiny

Clinical data suggests rotating injection sites weekly prevents lipodystrophy (fat tissue changes) while reducing localized tissue irritation that accumulates with repeated same-site injections
