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Typical candidates have a BMI of 30 or more and want to lose weight

Patients should maintain a low threshold for reporting new or different right upper quadrant pain to their healthcare provider

In addition, GLP-1R overexpression results in improved cognitive function in mice and GLP-1R knockout severely impairs cognitive ability (5, 117, 118)

Recent health insurance data from France are indicative of an elevated risk of medullary thyroid carcinoma in individuals treated with GLP-1RAs versus other glucose-lowering agents (35 cases, hazard ratio [HR] 1.78 [95% CI 1.043.05]) (78)