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performed a systematic review and meta-analysis of GLP-1-based therapies on MASLD/MASH outcomes, incorporating both clinical trials and real-world studies [63]
Although these changes in HR upon GLP-1 RA administration were subtle and the underlying mechanisms are unclear, further studies are necessary to elucidate the long-term effects of GLP-1 RAs primarily on HR and other related variables to clarify whether the elevated HR can be regarded as a transient reflex mechanism or whether it might in fact lead to poor cardiovascular outcomes in a diabetic population

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Starting GLP-1 injections can feel intimidating, but knowing where to inject and how to make it easy is key to staying consistent
