why do glp-1 agonists cause nausea and Anesthesia: Considerations and Cautions for CRNAs Nausea & Vomiting from GLP-1

GLP-1 (Glucagon-Like Peptide-1) is a natural hormone produced in the gut

When GLP-1 RAs started to be used, the first observations of certain occurrences led to misconceptions and erroneous conclusions regarding either the risks associated with the use of these drugs or the profiles of patients who would not benefit from these therapies

Moreover, tirzepatide (6.77 cm (8.97 to 4.57)), semaglutide (3.74 cm (5.25 to 2.24)), and liraglutide (2.30 cm (3.78 to 0.82)) were shown to be effective in reducing waist circumference (figure S6.2, figure S7.5, table S7.5, and table S8.5)

These studies cannot be compared directly head to head, due to differences in study design and timepoints at which weight was measured