glp-1 receptor agonist mechanism of action of agonists – My Endo Consult List of GLP-1 Receptor Agonists
Description
PMID 29677303
Na + and Ca 2+ accumulation in the heart, due to the increase in Na+/H+ exchanger (NHE), could cause a failing heart
The AMPLITUDE-O trial, which studied Efpeglenatide versus placebo with a mean follow-up of 1.81 years, demonstrated a significant 27% reduction in MACE
A good medical plan should protect muscle and function, not just reduce scale weight
