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Nicolau, J., Blanco-Anesto, J., Bonet, A., Flix-Jaume, J

Dual incretin (GIP/GLP-1) injection approved for diabetes, with strong weight-loss outcomes

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We found that AAV-mediated knockdown of hepatic CYP8B1 could block the T3 effects on the GLP-1 production, insulin and glucose levels, and oral glucose tolerance in either hypothyroid or euthyroid mice (Fig