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A Mayo Clinic study published in the Lancet Obstetrics found that women using tirzepatide alongside HRT achieved 17 percent weight loss compared to 14 percent with tirzepatide alone

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It is used off-label only under specialist advice, as potential risks include increased risk of haemorrhagic stroke and other adverse effects

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The standard of care included 49% of individuals receiving a sodium-glucose cotransporter-2 (SGLT2) inhibitors

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Based on animal studies, there may be potential risks to an unborn baby from exposure to tirzepatide during pregnancy

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