papillary thyroid cancer and glp-1 receptors (GLP-1R) are expressed in premalignant lesions in human GLP-1 Medications and Thyroid Cancer

But we want to lose as little muscle as possible and as much fat as possible, Kristin notes

In our practice, constipation is one of the most consistently reported problems on GLP-1 therapy, particularly in the first weeks of a new dose

A systematic review of over 94,000 adults seeking obesity treatment found that 14% had binge eating disorder on clinical interview and up to 26% reported moderate-to-severe binge eating on self-report measures ( Melville et al., Int J Eating Disorders, 2025 )

Standard GLP-1 restrictions apply, including a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 (MEN2)