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observed that, in vitro, exendin-4 may promote neurite outgrowth via both the ERK MAPK and the PI3K signaling pathways and may be able to rescue degenerating neurons [77]

86% of adults taking Wegovy lost 5% or more weight, compared to 31% taking placebo 69% of adults taking Wegovy lost 10% or more weight, compared to 12% taking placebo 51% of adults taking Wegovy lost 15% or more weight, compared to 5% taking placebo* About 1 in 3 adults lost 46 lb or more (20% weight loss) while only 1.7% of adults on placebo experienced the same weight loss

The main drawbacks are price (starting at $299/mo puts Willow above the market average) and geographic availability (33 states, not nationwide)

It also reduced pain by up to an average of 4.5 points (or 75.8 percent)