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She explained that lack of hydration can increase heat stroke, and people on GLP-1's need more hydration than others
Regarding newer agents, evidence from phase 2 trials indicates that the triple agonist retatrutide (GLP-1R/GIPR/GCGR) can achieve unprecedented weight loss of up to 24.4% (Jastreboff et al., 2023)
Regulation of adaptive behaviour during fasting by hypothalamic Foxa2
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