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In the STEP trials, semaglutide produced average weight loss of 1518% at the 2.4 mg maintenance dose, with approximately 80% of participants achieving clinically significant (5%) weight loss

In the ATTAIN-2 trial, participants lost an average of 22.9 lbs (10.5 percent) on the highest (36mg) dose of orforglipron, with A1C reduced by an average of 1.8 percent
The same online process reaches nearby communities too, including Tempe (2 mi), Guadalupe (3 mi), Ahwatukee Foothills (6 mi), so people across this corner of Arizona can start without a long drive

Head-to-head trials (CONCLUDE and BRIGHT) showed comparable glucose control between the two, with some differences in hypoglycemia patterns depending on the trial design
