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Those with significant medical co-morbidities, prior CSF diversion procedures, neurovascular stenting or optic nerve sheath fenestration, those currently using GLP-1 receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors or taking drugs that could reduce ICP were excluded

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A comprehensive plan combining these approaches provides the best functional and aesthetic outcomes

According to NICE guidance on type 2 diabetes management (NG28), healthcare professionals should counsel patients about expected side effects before initiating GLP-1 receptor agonist therapy, emphasising that most gastrointestinal symptoms are transient and manageable with appropriate strategies