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For them to work effectively, they need to be taken long-term

doi: 10.1016/j.numecd.2021.07.015 48 MarranoNBiondiGBorrelliACignarelliAPerriniSLaviolaLet al

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In additional analyses that used an alternative as-treated definition for drug use, the mean follow-up time among patients who started GLP1 receptor agonists was 1.8 years in the analysis with 90 day gap and tail periods, 2.6 years in the analysis with one year gap and tail periods, and 2.9 years in the analysis with two year gap and tail periods
