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Description
RET proto-oncogene testing MEN 2 is caused by germline mutations in the RET proto-oncogene
The tumors are usually papillary or mixed histologically, and tend to grow slowly, with a high frequency (50 -80%) of neck metastases, but with a relatively favorable prognosis
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At the primary 32-week endpoint, 82.0% of participants on 6 mg achieved at least 5% weight loss compared to 10.5% with placebo