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For people with type 2 diabetes who found semaglutide insufficient for blood sugar control or weight management, these numbers offer concrete evidence that tirzepatide provides a meaningful upgrade
Diabetes 66 , 235240 (2017)
In the STEP UP clinical trial, the 7.2 mg dose produced a mean weight loss of 20.7% at 72 weeks, compared with 17.5% at the previously approved 2.4 mg dose and 2.4% with placebo
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