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This case underscores the potential for tirzepatide to cause severe gastrointestinal dysmotility and fecal stasis, highlighting the importance of vigilance for bowel complications in patients on GLP-1 RAs who present with acute abdominal symptoms [15]

That said, everyones journey looks different

However, with the publication of the recent ADA guidelines, GLP-1 RAs are now recommended for the first time as an adjunctive therapy to lifestyle interventions for adults with T2D, particularly those who are overweight or obese and have NAFLD/MASLD (Level of evidence B)

Second, more weight loss is not automatically better for every patient