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Adherence to lifestyle modifications substantially impacts results

Novo's franchise for semaglutides brought in nearly $19 billion in net sales last year

Rare but potentially serious adverse effects include pancreatitis, gallbladder disease, acute kidney injury, and hypersensitivity reactions, although the overall incidence of these events is low

The GLP-1 receptor system is known to be expressed in areas of the brain involved in mood regulation, reward processing, and appetite control, including the hypothalamus and limbic system
