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Among the marketed large molecule injectable GLP-1 agonists, semaglutide, apart from weight-loss, is being studied for kidney disease and tirzepatide (a dual GLP-1 and GIP receptor agonist) is being evaluated for sleep apnea in Ph 3 clinical trials

Mandatory in advanced DR Reasonable in unstable DR (expert opinion) What This Means for Practice Semaglutide: Requires mandatory retinal workup, stabilization of PDR/DME, and cautious HbA1c pacing in moderate-severe DR

100% of participants confirmed DermaReverse was gentle enough for daily use

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