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Another triple agonist candidate, Hanmis efocipegtrutide (HM15211), is in a phase 1 trial for weight loss and in a phase 1b/2a for nonalcoholic fatty liver disease (NAFLD)
MIN6B1 were treated as INS-1 832/3 but in Krebs-HEPES-bicarbonate (KHB) buffer (140 mM NaCl, 3.6 mM KCl, 1.5 mM CaCl 2 , 0.5 mM MgSO 4 , 0.5 mM NaH 2 PO 4 , 2 mM NaHCO 3 , 10 mM HEPES, and 1% BSA
doi: 10.1111/jdi.12861
[89] In May 2026, the CHMP adopted a positive opinion, recommending a change to the terms of the marketing authorization for the medicinal product Wegovy
