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Description
The mechanism of action involves dual agonism at both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors

Those who stopped and switched to placebo regained a significant portion, with the majority regaining half or more of their lost weight within a year

Then the compounded supply they were using dries up or the cost becomes unsustainable or insurance drops coverage

Tirzepatide is not appropriate for individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
