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Additionally, it is advisable to keep a pain diary, noting the intensity of pain and the effectiveness of the medication, which can help healthcare providers make informed decisions about ongoing treatment

Additional clinical variables such as chronic kidney disease that could confound healing outcomes were also excluded to create a more homogeneous cohort

Constipation develops in up to 20% of patients because semaglutide slows intestinal motilitythe muscle contractions that move food through your digestive tract

BMJ 2026;392:s252
