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Negative-staining EM visualization displayed more particles with similar size (Supplementary information, Fig

With the development of genetic testing technologies such as genome-wide association studies (GWAS) and next-generation sequencing (NGS), it has been discovered that approximately 127 locus abnormalities in the human genome are associated with the onset and progression of obesity [4] , as along with more than 550 monogenic mutations related to obesity [5]

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A matched case-control study by Bakris et al of individuals with stage 3 or 4 CKD compared individuals with recurrent hyperkalemia over 12 months vs those who remained normokalemic after 5 years [20]