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Boletus edulis was identified as a rich source of selenoneine, a selenium analogue of ergothioneine, providing highly bioavailable antioxidant selenium ( Cyttaria espinosae , thereby enhancing its antioxidant capacity ( Pleurotus cystidiosus improved glucose metabolism and reduced inflammation by lowering TNF- and IL-1, increasing insulin and GLP-1 secretion, and inhibiting DPP-4 activity, demonstrating combined antidiabetic and anti-inflammatory benefits ( Several mushrooms also exhibit potent neuroprotective and cognitive-enhancing properties

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Rising cases of obesity, unhealthy diets, and lack of physical activity are major contributors to the growing burden of type 2 diabetes