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These hormones primarily work in the brain to reduce appetite and in the digestive tract to slow stomach emptying

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But managing the physical underpinnings of hunger is just one way semaglutide helps with weight management

2.4 Recommended Dosage in Patients with Renal Impairment The recommended dosage in patients with mild (CrCl greater or equal to 50 and less than 80 mL/min) renal impairment is the same as the recommended dosage for patients with normal renal function [see Warnings and Precautions (5.8), Use in Specific Populations (8.6), and Clinical Pharmacology (12.3)]