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These systems also support the transplantation of human peripheral blood mononuclear cells, macrophages, neutrophils, or iPSC-derived immune cells into immunocompromised or early embryonic zebrafish, facilitating the construction of inflammation models with a humanized immune background

Potential Biomarkers of the Mature Intervertebral Disc Identified at the Single Cell Level

309,310 The damaged esophageal squamous mucosal layers can be replaced with metaplastic columnar epithelium, which is more acid-resistant and contributed by CLDN 18, as found in patients with Barretts esophagus

doi: 10.1126/scisignal.2004652 85 LeeHJZhuangGCaoYDuPKimHJSettlemanJ